Finite size and finite temperature studies of the osp(1∣2)osp(1|2) spin chain

We study a quantum spin chain invariant by the superalgebra $osp(1|2)$. We derived non-linear integral equations for the row-to-row transfer matrix eigenvalue in order to analyze its finite size scaling behaviour and we determined its central charge. We have also studied the thermodynamical properties of the obtained spin chain via the non-linear integral equations for the quantum transfer matrix eigenvalue. We numerically solved these NLIE and evaluated the specific heat and magnetic susceptibility. The analytical low temperature analysis was performed providing a different value for the effective central charge. The computed values are in agreement with the numerical predictions in the literature.Comment: 26 pages, 2 figure

Effects of nucleus initialization on event-by-event observables

In this work we present a study of the influence of nucleus initializations on the event-by-event elliptic flow coefficient, $v_2$. In most Monte-Carlo models, the initial positions of the nucleons in a nucleus are completely uncorrelated, which can lead to very high density regions. In a simple, yet more realistic model where overlapping of the nucleons is avoided, fluctuations in the initial conditions are reduced. However, $v_2$ distributions are not very sensitive to the initialization choice.Comment: 4 pages, 5 figures, to appear in the Bras. Jour. Phy

Functional analysis of novel genes differentially expressed genes in heart/hemangioblast precursor cells (H/HPC)

info:eu-repo/semantics/publishedVersio

Impacts of in vivo and in vitro exposures to tamoxifen: comparative effects on human cells and marine organisms

Tamoxifen (TAM) is a first generation-SERM administered for hormone receptor-positive (HER+) breast cancer in both pre- and post-menopausal patients and may undergo metabolic activation in organisms that share similar receptors and thus face comparable mechanisms of response. The present study aimed to assess whether environmental trace concentrations of TAM are bioavailable to the filter feeder M. galloprovincialis (100 ng L-1) and to the deposit feeder N. diversicolor (0.5, 10, 25 and 100 ng L-1) after 14 days of exposure. Behavioural impairment (burrowing kinetic), neurotoxicity (AChE activity), endocrine disruption by alkali-labile phosphate (ALP) content, oxidative stress (SOD, CAT, GPXs activities), biotransformation (GST activity), oxidative damage (LPO) and genotoxicity (DNA damage) were assessed. Moreover, this study also pertained to compare TAM cytotoxicity effects to mussels and targeted human (i.e. immortalized retinal pigment epithelium - RPE; and human transformed endothelial cells - HeLa) cell lines, in a range of concentrations from 0.5 ng L-1 to 50 μg L-1. In polychaetes N. diversicolor, TAM exerted remarkable oxidative stress and damage at the lowest concentration (0.5 ng L-1), whereas significant genotoxicity was reported at the highest exposure level (100 ng L-1). In mussels M. galloprovincialis, 100 ng L-1 TAM caused endocrine disruption in males, neurotoxicity, and an induction in GST activity and LPO byproducts in gills, corroborating in genotoxicity over the exposure days. Although cytotoxicity assays conducted with mussel haemocytes following in vivo exposure was not effective, in vitro exposure showed to be a feasible alternative, with comparable sensitivity to human cell line (HeLa).info:eu-repo/semantics/publishedVersio